People who have trouble sleeping are six times more likely to develop diabetes and heart disease, a study of 20,000 people has suggested.
The latest findings, published in Nature Genetics, revealed that a faulty protein known as MT2, may disrupt the link between our 24 hour rhythms and release of the hormone insulin, leading to abnormal control of blood sugar which, as a result, may lead to type two diabetes.
Research showed that after three days of disrupted sleep, participants in the study started showing symptoms of diabetes, the Daily Mail reports.
“Blood sugar control is one of the many processes regulated by the body’s biological clock,” Professor Philippe Froguel, of Imperial College London, said. “This study adds to our understanding of how the gene that carries the blueprint for a key component in the clock can influence people’s risk of diabetes.”
“We found very rare variants of the MT2 gene that have a much larger effect than more common variants discovered before. Although each mutation is rare, they are common in the sense that everyone has a lot of very rare mutations in their DNA. Cataloguing these mutations will enable us to much more accurately assess a person’s risk of disease based on their genetics.”
Dr Iain Frame, Director of Research at Diabetes UK, said: “Genetic studies like this one are useful as they can help us understand how a person’s genetic makeup can influence their risk of developing type two diabetes.”
“What we can be sure of now is that eating a balanced diet rich in fruit and vegetables, maintaining a healthy weight and being more physically active can help to reduce the risk of developing type two diabetes as well as help people with the condition to manage it more effectively and lower the likelihood of developing serious complications.”
Aside from a risk of diabetes, other health risks associated with lack of sleep include:
- putting on weight unnecessarily, because a lack of sleep eliminates the hormone in your body that regulates appetite
- an increase in cortisol, which slows the production of collagen meaning you wrinkle faster
- increased chance of a heart attack by 100 per cent because your heart works overtime
- a decline in IQ for each successive day you sleep badly
In a 2010 survey by Recourse and Teacher Support Network, many staff revealed that their sleep pattern suffered as a result of stress and anxiety in the workplace. Others blamed workload for their lack of sleep leading to poor health, a loss in concentration and a bad temper.
“I work a 90 hour week. I don’t have time to sleep. Staff are depressed and I am always criticised for not doing enough. I have seen my family grow up without me,” one respondent stated.
Another commented: “Extreme lack of sleep since September has greatly affected my health. I have had little time for family, friends or a relationship. I feel rather miserable about the situation, but see no alternative, other than to get through the year and hope for better in the summer. Tiredness has resulted in me becoming short-tempered and resentful for the job.”
If you believe lack of sleep has affected your health and wellbeing and you need somebody to talk to, call our free, confidential Support Line on: 0808 802 03 04.
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by Victoria Bamber



